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The principal cytochrome P450 isoenzyme included seems to be CYP2E1, with CYP1A2 and CYP3A4 as added pathways. Approximately 85% of an oral dose seems within the urine within just 24 several hours of administration, most since the glucuronide conjugate, with modest quantities of other conjugates and unchanged drug (see OVERDOSAGE) for toxicity deta